Associate Scientist

ORION GROUP

CORK

Orion Group Life Sciences are looking for an Associate Scientist for our Multinational Pharmaceutical client based in the Cork area on an initial 10-month contract with the potential to extend. Job Purpose. Reporting to the Bioassay Team Lead in Cork the person will support testing and review of a wide range of bioassay and process impurity methods used in the release and stability testing of the large molecule clinical pipline. The department is responsible for release and stability testing of both drug substance and drug product to supporting the client's large molecule portfolio of drugs that in clinical phase. In addition, the department is also the centre of expertise for stability management of the large molecule clinical portfolio. Main Responsibilities of the role. The Bioassay and Early Development Stability team is a diverse team of Scientists that work on a variety of laboratory based methods including ELISA's, cell based assays and FRET binding assays. The laboratory also supports ID testing and is responsible for a wide range of activities supporting residual process impurities such a Protein A, DNA and Host Cell Proteins. The Bioassay and Early Development Stability team is responsible for analytical support through troubleshooting, investigations, manufacturing support and analytical method transfer. Ensure compliance with applicable cGMP and other business compliance regulations. Execution of a wide range of bioassay methods and techniques (ELISA, cell based assays, FRET and residual process impurity assays. Second scientist review of a wide range of bioassay methods and techniques (ELISA, cell based assays, FRET and residual process impurity assays. Completion of documentation in adherence to GMP. Participate in analytical method technology transfer of new bioassays methods into the department, including validation and qualification activities. Laboratory support activities (e.g. reagent qualification), routine passaging of cell lines and general housekeeping. Support troubleshooting and investigations. Support other projects as assigned, e.g. continuous improvement, automation and operational excellence. Desired Experience and Background of the successful candidate. A minimum of a Degree in Molecular Biology, Biochemistry, Pharmacy or related scientific field is required. Practical analytical laboratory experience in a GLP/GMP environment is advantageous. Experience of Bioassay/Cell Culture experience is advantageous. Familiar with applicable cGMP and other business compliance regulations. Customer focus and results and performance driven. Ability to work well within team structures and provide leadership. Knowledge of computer programs such as MS Word, Excel and Minitab. Good understanding of quality and attention to detail. #BioTherapeutics #bioassay #pharma #pharmaceutical #R&D #science&research #laboratory #drug #product #Biochemistry #GMP #GLP. For more information on this role, call Shane O' Neill on 353 (0) 212063407 or email Shane.ONeill@orioneng.com@orioneng.com for a completely confidential chat about this role and other opportunities using the reference number: 930038. Our role in supporting diversity and inclusion. As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.

1522 days ago